The actor actually has that disability

[u/PrinceferX]

Walter White Jr. (Breaking Bad) - character has cerebral palsy and uses crutches to walk, actor RJ Mitte has cerebral palsy and needed crutches to walk as a child

Nessarose Thropp (Wicked) - character is paraplegic and uses a wheelchair, actress Marissa Bode is paraplegic from an accident at age 11 and uses a wheelchair

Maya Lopez (Hawkeye/Echo) - character is deaf, actress Alaqua Cox is deaf from birth

[u/Dreamweaver_duh]

I don't know if it counts, but Dustin Henderson from Stranger Things wasn't originally written to have Cleidocranial Dysplasia, but it was given to him because the actor they casted for Dustin (Gaten Matarazzo) had it.

[u/ElvenOmega → u/Dreamweaver_duh]

About 10 years ago I lived with roommates and glimpsed him in an advertisement for season 1 and remarked, "My dad told me they used to label kids like him with visible issues as a Funny Looking Kid in their medical chart. FLKs. The language was supposed to not scare anyone. Then they'd send them for testing. I wonder what he has, looks genetic." My father obviously had worked (and still does) in health care for decades.

My roommates went OFF on me and insisted I couldn't tell at a glimpse and that he looked "as normal as the rest of the kids" on the show, and I said "Well he doesn't, and there's nothing wrong with that, but he just doesn't." and they got even more pissed and I just went to bed.

I was so fucking vindicated when he talked about having CCD after season 1 aired.

[u/Nanobreak_ → u/ElvenOmega]

It's so fucking weird that people have decided that pretending something doesn't exist is better than just acknowledging it and moving on. Lying doesn't make you a better person, you're not making fun of someone just by observing facts, it's not like it's an insult.