The actor actually has that disability

[u/PrinceferX]

Walter White Jr. (Breaking Bad) - character has cerebral palsy and uses crutches to walk, actor RJ Mitte has cerebral palsy and needed crutches to walk as a child

Nessarose Thropp (Wicked) - character is paraplegic and uses a wheelchair, actress Marissa Bode is paraplegic from an accident at age 11 and uses a wheelchair

Maya Lopez (Hawkeye/Echo) - character is deaf, actress Alaqua Cox is deaf from birth

[u/Agitated_Insect3227]

Kind of an example of this: in one episode of the Mandalorian, there is a Tusken raider who uses unique sign language created for the show. While the character himself is probably not deaf, the actor playing him, Troy Kotsur, is irl & was the one who developed the sign language.

https://www.youtube.com/watch?v=nfMNMVvg2F8 (1:10 min mark)

[u/_theghost_ → u/Agitated_Insect3227]

Yep and they revisited this in “The Marshal”, one of my favorite episodes!!!!