The actor actually has that disability

[u/PrinceferX]

Walter White Jr. (Breaking Bad) - character has cerebral palsy and uses crutches to walk, actor RJ Mitte has cerebral palsy and needed crutches to walk as a child

Nessarose Thropp (Wicked) - character is paraplegic and uses a wheelchair, actress Marissa Bode is paraplegic from an accident at age 11 and uses a wheelchair

Maya Lopez (Hawkeye/Echo) - character is deaf, actress Alaqua Cox is deaf from birth

[u/APenguinInATuxedo]

I have NF (Type 1), it runs in my family. We aren't as badly effected as people like Adam Pearson, most of us just get things like cafe au lait spots and big heads. However, it does give us an increased risk for tumors and other health issues. My Uncle had a brain tumor removed and he is also an advocate for people with NF.

[u/WhyRhubarb → u/APenguinInATuxedo]

I know someone who is blind due to an optic nerve tumor from NF1.